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DNA Polymerase Theta Shown to Reverse Transcribe RNA


Science & Medicine News Jun 27, 2021 by BioCompare


Researchers from Thomas Jefferson University have reportedly found evidence that RNA segments can be written back into DNA, which potentially challenges the central dogma in biology and could have wide implications affecting many fields of biology.

tags: #rna #dna #virii #jefferson #polymerase #reverse-transcriptase #thomas

"This work opens the door to many other studies that will help us understand the significance of having a mechanism for converting RNA messages into DNA in our own cells," says Richard Pomerantz, senior author of a paper published in Science Advances recently. "The reality that a human polymerase can do this with high efficiency, raises many questions." For example, this finding suggests that RNA messages can be used as templates for repairing or re-writing genomic DNA.

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