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SARS-CoV-2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro |
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the coronavirus disease 2019 (COVID-19) pandemic, severely affecting public health and the global economy. Adaptive immunity plays a crucial role in fighting against SARS-CoV-2 infection and directly influences the clinical outcomes of patients. |
Oct 13, 2021
by
MDPI
Science & Medicine Blogs |
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Designer Cytokine Makes Paralyzed Mice Walk Again |
Summary: Protein hyper-interleukin-6, a "designer protein" that has to be produced via genetic engineering, enabled a paralyzed mouse to walk again. Spinal cord injuries caused by sports or traffic accidents often result in permanent disabilities such as paraplegia. |
Jan 16, 2021
by
Neuroscience News
Science & Medicine News |
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Cellular survival over genomic perfection |
Damage to DNA occurs continuously. DNA quality control mechanisms, such as DNA repair and replicative pathways, mitigate that damage and preserve the DNA sequence. Mutations are believed to arise when DNA lesions are not repaired appropriately, and they are thought to be an indicator of ineffectual DNA quality control. |
Nov 24, 2019
by
Science
Science & Medicine Blogs |