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SARS-CoV-2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the coronavirus disease 2019 (COVID-19) pandemic, severely affecting public health and the global economy. Adaptive immunity plays a crucial role in fighting against SARS-CoV-2 infection and directly influences the clinical outcomes of patients.

Oct 13, 2021 by MDPI
Science & Medicine Blogs
Brain imaging before and after COVID-19 in UK Biobank

There is strong evidence for brain-related pathologies in COVID-19, some of which could be a consequence of viral neurotropism. The vast majority of brain imaging studies so far have focused on qualitative, gross pathology of moderate to severe cases, often carried out on hospitalised patients.

Jun 11, 2021 by medRxiv
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Vaccine-driven virulence evolution: consequences of unbalanced reductions in mortality and transmission and implications for pertussis vaccines

Many vaccines have heterogeneous effects across individuals. Additionally, some vaccines do not prevent infection, but reduce disease-associated mortality and transmission. Both of these factors will alter selection pressures on pathogens and thus shape the evolution of pathogen virulence. We use a ...

Dec 16, 2019 by PubMed
Science & Medicine Blogs
Common cold virus 'helps destroy' bladder cancer

A strain of the common cold virus could help infect and kill bladder cancer cells, a small study suggests. All signs of the disease disappeared in one patient, and in 14 others there was evidence that cancer cells had died.

Jul 05, 2019 by Philippa Roxby at BBC News
Science & Medicine News



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