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Scientists discover how rogue communications between cells lead to Leukaemia

Posted on 6 February 2020 New research has deciphered how rogue communications in blood stem cells can cause Leukaemia. The discovery could pave the way for new, targeted medical treatments that block this process. Blood cancers like leukaemia occur when mutations in stem cells cause them to produce too many blood cells.

Feb 09, 2020 by University of York
Science & Medicine News
Immune cell which kills most cancers discovered by accident by British scientists in major breakthrough

Prof Sewell said the 'right people' are now interested in developing the potential new therapy and said progress could now move 'quite fast'. The team says human trials on terminally ill patients could begin as early as November if the new treatment passes further laboratory safety testing.

Jan 20, 2020 by Sarah Knapton via Telegraph.co.uk
Science & Medicine News
Small, thin metal mesh loaded with cancer-fighting immune cells shrinks tumors in preclinical models of ovarian cancer

Micropatterned nickel titanium (commonly known as nitinol) thin films with complex designs, high structural resolution and excellent biocompatibility can be cheaply fabricated using magnetron sputtering. Here, we show that these benefits can be leveraged to fabricate micromesh implants that are loaded with tumour-specific human chimeric antigen receptor (CAR)-T cells for the treatment of solid tumours.

Dec 16, 2019 by Coon, .et al. via Nature Biomedical Engineering
Science & Medicine Blogs
'Dual login' mechanism found to resist fungal infection in cells

BLOOMINGTON, Ind. -- Indiana University researchers have identified a mechanism involving the body's ability to resist fungal infection. The work could help advance research on cancer therapies that use the body's own immune system to fight disease. In a study published Nov.

Nov 24, 2019 by Kevin Fryling via News at IU Bloomington
Science & Medicine News
Cellular survival over genomic perfection

Damage to DNA occurs continuously. DNA quality control mechanisms, such as DNA repair and replicative pathways, mitigate that damage and preserve the DNA sequence. Mutations are believed to arise when DNA lesions are not repaired appropriately, and they are thought to be an indicator of ineffectual DNA quality control.

Nov 24, 2019 by Science
Science & Medicine Blogs
Brain tumors form synapses with healthy neurons

Stanford researchers made a groundbreaking discovery about brain tumors. The study reports high-grade gliomas form synapses which hijack electrical signals from healthy neurons in the brain, promoting tumor growth. Interrupting the signals with a drug currently used to treat epilepsy reduces the tumor growth in mouse models.

Sep 18, 2019 by Neuroscience News
Science & Medicine News
Common cold virus 'helps destroy' bladder cancer

A strain of the common cold virus could help infect and kill bladder cancer cells, a small study suggests. All signs of the disease disappeared in one patient, and in 14 others there was evidence that cancer cells had died.

Jul 05, 2019 by Philippa Roxby at BBC News
Science & Medicine News
A Completely New Way to Picture DNA in Cells

Just how are things organized in a living cell? What's next to what, in three dimensions? That is, of course, a really hard question to answer, but we're going to have to be able to answer it in a lot of contexts (and at high resolution) if we're ever going to understand what's going on down there.

Jun 29, 2019 by Derek Lowe via Science Translational Medicine
Science & Medicine Blogs



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